It may be more common in those with sweaty palms due to localised hyperhidrosis. Some individuals have a family history of the disorder. Keratolysis exfoliativa. Lack of research and mild severity is the reason even no genetical abnormality is recorded yet. Keratolysis exfoliativa normally appears during warm weather. Primary Care Dermatology Society. Exfoliative keratolysis can also be called “focal palmar peeling” or “keratolysis exfoliativa.” In generic terms it’s known as the “skin peeling disease.” One big problem with EK is that sufferers often delay a doctor’s visit because the condition is not usually painful. Contact us to sponsor a DermNet newsletter. Treatment of Exfoliative keratolysis. Keratolysis exfoliativa is more common during the summer months in about 50% of affected individuals. Causes. The cause of keratolysis exfoliativa is unknown. Keratolysis exfoliativa is distinct from the following conditions. Exfoliative keratolysis could be triggered by genetic disposition to skin infections; this may happen after skin is being exposed to some outside factors. It is thought that for some reason the desmosomes on the corneocytes separate from each other prematurely. The leading primary care society for dermatology and skin surgery. Sometimes on the ends of the fingers, the split in the skin is deeper, in which case the skin feels hard and numb and takes longer to peel off. Hausauer AK, Cohen DE. https://en.wikipedia.org/w/index.php?title=Keratolysis_exfoliativa&oldid=951609669, Creative Commons Attribution-ShareAlike License, This page was last edited on 18 April 2020, at 00:10. Sponsored content: melanomas are notoriously difficult to discover and diagnose. Due to excessive sweating and friction, in for example athletic shoes, the skin can start to exfoliate. During the second cycle of treatment, diffuse erythroderma, desquamation, and peripheral blood eosinophilia developed. Keratolysis exfoliativa normally appears during warm weather. In most cases exfoliation resolves spontaneously and no lasting damage is seen. Photochemotherapy – a technique used to boost the immune system. If you have any concerns with your skin or its treatment, see a dermatologist for advice. Other factors that can cause exfoliation are detergents and solvents. These blisters can be peeled off very easily and will leave reddish, tender areas. shows cleavage and partially degraded corneodesmosomes within the stratum corneum. Supportive investigations may be undertaken. The loss of this horny layer of the skin, which protects the underlying layers, leaves the skin more vulnerable to dryness and cracking. Keratolysis exfoliativa (dyshidrosis lamellosa sicca): a distinct peeling entity. James, William; Berger, Timothy; Elston, Dirk (2005). Br J Dermatol. Your email address will not be published. Epub 2012 Oct 5. Topics A–Z There is no severe harm from this condition recorded yet. PubMed PMID. The first sign of keratolysis exfoliativa is one or more superficial air-filled blisters on the fingers or palms. However, they are not generally itchy. Note that this may not provide an exact translation in all languages, breadcrumbs Exfoliative keratolysis also known as ‘keratolysis exfoliativa’, and ‘focal palmar peeling’ is a common skin condition that causes the skin of the palms and soles of foot to peel off. doi: 10.1111/j.1365-2133.2012.11175.x. » Exfoliative keratolysis. Eventually normal skin forms, but frequently exfoliative keratolysis recurs within a few weeks. Most often this condition recurs in a matter few weeks and seldom reported due to its largely asymptomatic nature. The symptoms are aggravated by exposure to irritants including water, soap, detergents and solvents. Recurrent focal palmar peeling. DermNet NZ does not provide an online consultation service. Keratolysis exfoliativa generally presents in young active adults. Normally, exfoliation is restricted to a particular area and normal skin will replace the exfoliated parts, so no treatment is needed. , 1999. Keratolysis exfoliativa does not improve with topical steroids, unlike hand dermatitis. See smartphone apps to check your skin. In severe cases, photochemotherapy is an option. Keratolysis exfoliativa is a common skin condition in which there is focal peeling of the palms and less often the soles. It is often misdiagnosed as chronic contact dermatitis or psoriasis. With your help, we can update and expand the website. Skin Care Blogs by DermaTalk. 2012 Nov;167(5):1076–84. pii: 13030/qt6mv338nx. Since keratolysis exfoliativa is caused by friction, detergents, and solvents, these factors should be avoided. These peeled areas lack a normal barrier function and may become dry and cracked. No immediate cause has been associated with Exfoliative Keratolysis to … If you have any concerns with your skin or its treatment, see a dermatologist for advice. Keratolysis exfoliativa (also known as "lamellar dyshidrosis",[1] "recurrent focal palmar peeling",[2] "recurrent palmar peeling"[1]:212[2]) is a sometimes harmless, sometimes painful skin condition that can affect the focal surface of the fingers and/or the palm or soles of the feet. Other factors that can cause exfoliation are detergents and solvents. Rash in Corner of Mouth: Angular Cheilitis and its Treatment, Heat rash in Babies: Best ways to Treat and Prevent, Minocycline Topical Foam 1.5% Approved by FDA for Rosacea, What is Maskne (Mask Acne): Its Treatment and Prevention, Use emollient hand creams, which contain silicone, lactic acid or urea. Exfoliative keratolysis aggravates during summer, and most often affects teenagers. Keratolysis exfoliativa — codes and concepts. Creams, especially those with silicone and lactic acid are also helpful. No genetic abnormality has been detected to date (2018). Right now we don't know the cause behind it. Treatment was initiated with 1,000 mg/m 2 of cyclophosphamide and 300 mg/m 2 of carboplatin on day 1, as well as 10 μg/kg of granulocyte-macrophage colony-stimulating factor every 12 hours on days −6 to −2 and days 2 to 15 three weeks postoperatively. Lee YC, Rycroft RJ, White IR, McFadden JP. It is not sure whether it is from the salt water or whether it is from some bacteria from fish. Exfoliative Keratolysis can rarely present as painful where it leaves behind red inflamed underlying layers of skin. DermNet NZ does not provide an online consultation service. PubMed PMID: Chang YY, van der Velden J, van der Wier G, et al. The blisters burst to leave expanding collarettes of scale and circular or oval, tender, erythematous peeled areas. Home Australas J Dermatol. Microscopy reveals cleavage within the outside horny layer of skin, the stratum corneum. It is not a severe skin disorder. DermNet provides Google Translate, a free machine translation service. 2015 Dec 16;21(12). Tension, stress might also cause the skin problems or aggravate any underlying instances of skin infections. The first sign of keratolysis exfoliativa is one or more superficial air-filled blisters on the fingers or palms. On the other hand, some patients experience cracking and even bleeding in extreme cases. It may be more common in those with sweaty palms due to localised hyperhidrosis. 1996 Aug;37(3):143–4. Due to excessive sweating and friction, in for example athletic shoes, the skin can start to exfoliate. Keratolysis exfoliativa is diagnosed clinically. You can't! Updated by Dr Oakley, December 2018. Another very common cause has been reported from salt water fishermen, who often suffer from these symptoms. Author: Dr Amanda Oakley, Dermatologist, Hamilton, New Zealand, 1999. There can be multiple layers of peeling skin (lamellae). It is also known as exfoliative keratolysis, dyshidrosis lamellosa sicca, and focal palmar peeling. [Sponsored content]. Eventually normal skin forms, but frequently exfoliative keratolysis recurs within a few weeks. » Dermatol Online J. Updated by Dr Oakley, December 2018. Another very common cause has been reported from salt water fishermen, who often suffer from these symptoms. Keratolysis exfoliativa is more common during the summer months in about 50% of affected individuals. [3] It is characterized by dry skin and superficial, air-filled blisters. After skin is being exposed to some outside factors Amanda Oakley, dermatologist, Hamilton, New Zealand 1999... Function and may become dry and cracked been reported from salt water or whether is. May not provide an online consultation service of skin infections diffuse erythroderma, desquamation, and solvents might also the. An exact keratolysis exfoliativa mayo clinic in all languages, breadcrumbs Home » Topics A–Z » exfoliative could... These factors should be avoided is also known as exfoliative keratolysis barrier function and may become dry and.... 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